Management of erythroblastosis fetalis

The practical management of the problem of erythroblastosis depends primarily on the prenatal determination of which pregnancies might result in an erythroblastotic infant. The physician primarily concerned with the care of the child must attend the delivery of every Rh-negative woman whose serum contains anti-Rh antibodies. At present, prompt confirmation of the suspected diagnosis immediately following birth and immediate exchange transfusion in infants with laboratory or clinical evidence of the disease are necessary to reduce morbidity and prevent kernicterus.

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