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Head and neck synovial cell sarcoma.

F R Amble¹, K D Olsen, A G Nascimento

¹Department of Otolaryngology, Mayo Clinic, Rochester, MN 55905.

Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery

|November 1, 1992

Summary

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Synovial cell sarcoma, a rare cancer in young adults, often presents as a neck mass and can be misdiagnosed. Early detection and wide surgical removal improve patient prognosis.

Area of Science:

Oncology
Pathology
Surgical Oncology

Background:

Synovial cell sarcoma is a rare malignancy affecting young individuals.
Diagnosis can be challenging, with a significant rate of initial mispathologizing.
A painless neck mass is the most frequent initial clinical presentation.

Observation:

This study reviewed 14 patients diagnosed with synovial cell sarcoma over 30 years.
Patient ages ranged from 12 to 43 years.
One-third of patients initially received incorrect pathological diagnoses.

Findings:

Painless neck mass was the most common presenting symptom.
Treatment involved surgical excision alone or combined with radiation therapy.
Recurrence or metastasis occurred between 4 and 62 months post-initial treatment.

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Long-term follow-up is crucial, as 4 of 9 patients followed over 5 years succumbed to the disease.

Favorable prognostic indicators included early diagnosis and wide surgical excision.

Implications:

Highlights the diagnostic challenges and the need for accurate pathological assessment.
Emphasizes the importance of long-term patient monitoring for recurrence or metastasis.
Underscores the benefit of prompt diagnosis and aggressive surgical management in improving outcomes for synovial cell sarcoma.