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Peripheral T-cell lymphoma involving the placenta
P J Kurtin1, T A Gaffey, T M Habermann
1Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905.
Background:
Placental involvement by maternal malignant lymphoma is a rare complication of pregnancy.
Methods:
The case of a 29-year-old woman found to have placental involvement by peripheral T-cell lymphoma (PTCL) diagnosed by morphologic study, immunoperoxidase stains, and molecular genetic studies is reported.
Results:
The lymphoma was pathologic Stage IVB and although there were no adverse consequences for the child, but the neoplasm progressed rapidly during the postpartum period.
Conclusions:
The clinical course suggested that the immunologic changes of the pregnancy exerted a lymphoma-suppressive effect on the lymphoma. The authors know of no other report of a patient with placental involvement by PTCL.