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Acute calcific periarthritis in scleroderma.

A G Fam1, K P Pritzker

  • 1Division of Rheumatology, Sunnybrook Health Science Centre, Toronto, ON, Canada.

The Journal of Rheumatology
|October 1, 1992
PubMed
Summary
This summary is machine-generated.

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This study presents three patients with CREST syndrome and acute calcific periarthritis. Periarticular calcifications in scleroderma patients are less likely to resolve after acute attacks compared to idiopathic cases.

Area of Science:

  • Rheumatology
  • Dermatology
  • Crystal-induced Arthropathies

Background:

  • Limited cutaneous scleroderma, also known as CREST syndrome, is a connective tissue disease.
  • Acute calcific periarthritis is an inflammatory condition characterized by calcium crystal deposition.
  • The association between CREST syndrome and acute calcific periarthritis is not well-defined.

Observation:

  • Three patients with both CREST syndrome and acute calcific periarthritis were identified.
  • One patient presented with bursal effusion containing calcium hydroxyapatite crystals.
  • The clinical presentation included acute inflammatory episodes suggestive of periarthritis.

Findings:

  • Patients with scleroderma-associated acute calcific periarthritis exhibited "chalky" bursal effusions.

Related Experiment Videos

  • Calcium hydroxyapatite crystals were identified in the bursal effusion.
  • Resorption of periarticular calcifications was less frequent and incomplete following acute attacks in these patients compared to idiopathic cases.

    • Implications:

    • These findings suggest a distinct pattern of calcific periarthritis in patients with CREST syndrome.
    • The incomplete resolution of calcifications may have implications for long-term joint health and management in scleroderma patients.
    • Further research is warranted to understand the underlying mechanisms and optimize treatment strategies.