Related Experiment Videos
Antilipoxygenase activity of amyrin triterpenes
1Department of Anatomy and Physiology, Royal Melbourne Institute of Technology, Bundoora, Australia.
Research Communications in Chemical Pathology and Pharmacology
|December 1, 1992
Abstract:
Triterpenes--alpha-amyrin acetate, beta-amyrin acetate and beta-amyrin were tested for their effects on the synthesis of 5-lipoxygenase products in human neutrophils. All the triterpenes reduced 5-HETE synthesis without effect on LTB4 synthesis. The relative effects suggest that 5-HETE inhibition can explain the antiarthritic activity possessed by these compounds.