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Updated: Feb 8, 2026

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Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
Published on: November 20, 2015
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[The effect of hypoxia on the function of the hypothalamic neurosecretory system in rats]
Abstract:
Adaptation to intense hypoxia occurs owing to activation of vasopressin-synthetizing magnocellular neurons of the hypothalamus' paraventricular nucleus. The stability of the organism resistance against hypoxia seems to result from highly active state of the CRF and CRF/vasopressin-synthetizing neurons of the parvocellular portion of the paraventricular nucleus controlling the pituitary-adrenal axis.
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