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Molecular cloning and characterization of a mouse alpha 2C2 adrenoceptor subtype gene
W M Chen1, A C Chang, B J Shie
1Institute of Microbiology and Immunology, Neuroscience and Clinical Medicine, National Yang-Ming Medical College, Taipei, Taiwan, ROC.
Biochimica Et Biophysica Acta
|December 29, 1992
Abstract:
A clone MA2C2 encoding the murine homologue of adrenoceptor alpha 2C2 was isolated from a mouse genomic library using a subtype specific probe. The nucleotide and the deduced amino acid sequences derived from an ApaI fragment (2 kb) of the clone reveal a single open reading frame encoding a putative receptor protein of 455 amino acids. The 5' untranslated region (0.5 kb) sequenced is characterized by high GC content and CpG island count.