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Related Experiment Videos

Hepatic resection for hepatocellular carcinoma.

M Suenaga1, A Nakao, A Harada

  • 1Surgical Service, Nagoya Memorial Hospital, Japan.

World Journal of Surgery
|January 1, 1992
PubMed
Summary

Hepatic resection for hepatocellular carcinoma showed varying survival rates based on surgical approach and liver condition. Segmentectomy offered better outcomes than subsegmentectomy in patients with cirrhosis.

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Topic: Incisional Hernia - "Easy case" as daily case: open vs lap, where the mesh, which fixation…in center midline cases.

Hernia : the journal of hernias and abdominal wall surgery·2015

Area of Science:

  • Hepatobiliary Surgery
  • Surgical Oncology
  • Gastroenterology

Background:

  • Hepatocellular carcinoma (HCC) is a primary liver malignancy.
  • Hepatic resection is a curative treatment option for HCC.
  • The impact of surgical extent on outcomes in cirrhotic vs. non-cirrhotic patients requires further elucidation.

Purpose of the Study:

  • To evaluate the outcomes of hepatic resection for HCC in patients with and without cirrhosis.
  • To compare the efficacy of different resection types (lobectomy, segmentectomy, subsegmentectomy) in HCC treatment.
  • To identify prognostic factors influencing survival and recurrence after HCC resection.

Main Methods:

  • Retrospective analysis of 118 patients who underwent hepatic resection for HCC between 1979 and 1987.

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  • Categorization of patients based on the presence of cirrhosis and the extent of hepatic resection.
  • Comparison of operative mortality, survival rates, and tumor recurrence rates across different surgical groups.

    • Main Results:

    • Operative mortality was 11% in cirrhotic patients and 5% in non-cirrhotic patients.
    • Five-year survival rates for HCC with cirrhosis varied: lobectomy (20.0%), segmentectomy (57.6%), and subsegmentectomy (24.0%).
    • Segmentectomy demonstrated a lower tumor recurrence rate than subsegmentectomy. Multiple lesions, large tumors (>5 cm), and vascular invasion were poor prognostic indicators.

    Conclusions:

    • Hepatic resection is feasible for HCC, with segmentectomy showing promising survival and recurrence rates in cirrhotic patients.
    • Extent of resection and tumor characteristics significantly influence patient outcomes.
    • Repeat resection for recurrent HCC limited to the residual liver offers improved survival compared to other treatments.