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Updated: Aug 17, 2026

The Determination of Protease Specificity in Mouse Tissue Extracts by MALDI-TOF Mass Spectrometry: Manipulating PH to Cause Specificity Changes
Published on: May 25, 2018
[The behavior of trypsin-like proteases in sulcus fluid]
A Gerbatsch1, W Schwab, F Herrmann
1Institut für Pathologische Biochemie, Medizinische Akademie Carl-Gustav-Carus, Dresden.
Abstract:
The present study shows results aimed at determining whether levels of a trypsin-like protease in gingival crevicular fluid are associated with disease activity as assessed by the level of gingival inflammation and probing attachment loss. Maximum enzyme level was significantly elevated by groups with gingival inflammation and periodontal destruction. In a long-time study we find a decrease of enzyme activity with clinical therapy by scaling and root planning.

