Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Obesity increases risk for diabetes.

G A Bray1

  • 1Pennington Biomedical Research Center, Baton Rouge, Louisiana 70808.

International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity
|December 1, 1992
PubMed
Summary

Obesity significantly increases diabetes risk, especially in older adults and those with a family history. Factors like obesity duration, magnitude, and abdominal fat are key contributors.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effect of pioglitazone on body composition and bone density in subjects with prediabetes in the ACT NOW trial.

Diabetes, obesity & metabolism·2013
Same author

Diet type and changes in food cravings following weight loss: findings from the POUNDS LOST Trial.

Eating and weight disorders : EWD·2012
Same author

Effect of diet composition on energy expenditure during weight loss: the POUNDS LOST Study.

International journal of obesity (2005)·2011
Same author

Sensitivity to the satiating effects of exendin 4 is decreased in obesity-prone Osborne-Mendel rats compared to obesity-resistant S5B/Pl rats.

International journal of obesity (2005)·2010
Same author

Effect of a 3-day high-fat feeding period on carbohydrate balance and ad libitum energy intake in humans.

International journal of obesity (2005)·2010
Same author

Determinants of glucose tolerance in impaired glucose tolerance at baseline in the Actos Now for Prevention of Diabetes (ACT NOW) study.

Diabetologia·2009

Area of Science:

  • Endocrinology
  • Metabolic Health
  • Public Health

Background:

  • Obesity is a growing global health concern.
  • Diabetes mellitus is a major comorbidity associated with obesity.
  • Understanding the interplay between obesity and diabetes is crucial for public health strategies.

Purpose of the Study:

  • To review the relationship between obesity and the development of diabetes mellitus.
  • To identify key factors that mediate the risk of diabetes in obese individuals.

Main Methods:

  • Literature review of studies examining obesity and diabetes.
  • Analysis of demographic factors (age) and their correlation with obesity and diabetes.
  • Evaluation of obesity characteristics (duration, magnitude, abdominal fat) and their impact on diabetes risk.
  • Consideration of genetic predisposition (family history) in the obesity-diabetes link.

Main Results:

  • Older individuals exhibit higher rates of both obesity and diabetes.
  • Increased duration and magnitude of obesity are directly correlated with elevated diabetes risk.
  • Abdominal obesity is a significant risk factor for developing diabetes mellitus.
  • Family history of diabetes mellitus modulates the risk associated with obesity.

Conclusions:

  • Obesity is a primary risk factor for diabetes mellitus.
  • Age, obesity duration and magnitude, abdominal fat distribution, and family history are critical determinants in the development of diabetes in obese individuals.
  • These findings underscore the importance of weight management in diabetes prevention, particularly in at-risk populations.

Related Experiment Videos