Related Experiment Video
Updated: Aug 11, 2026

In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses
Published on: March 30, 2015
[Computed tomography of retroperitoneal neoplasms]
1Cancer Hospital, Chinese Academy of Medical Sciences, Beijing.
Computed tomography (CT) can help identify retroperitoneal tumors, differentiating between malignant and benign types. Key CT features aid in diagnosing liposarcoma and neural tumors, guiding treatment and follow-up strategies.
Area of Science:
- Radiology
- Oncology
- Medical Imaging
Background:
- Retroperitoneal neoplasms represent a diverse group of tumors.
- Accurate preoperative diagnosis is crucial for effective management.
- Computed tomography (CT) is a primary imaging modality for evaluating these masses.
Purpose of the Study:
- To review CT findings in retroperitoneal neoplasms.
- To correlate CT features with tumor histology (malignant vs. benign).
- To identify imaging characteristics predictive of specific tumor types and resectability.
Main Methods:
- Retrospective review of CT scans from 50 cases with 51 retroperitoneal tumors.
- Analysis of tumor characteristics including size, shape, density, margins, enhancement, and relationship to adjacent structures.
- Correlation of CT findings with histopathological diagnoses.
Main Results:
- 55% malignant and 45% benign tumors identified.
- Malignant tumors: MFH and liposarcoma most common. Benign tumors: neural origin most common.
- CT features like well-defined margins (benign) vs. irregular shape and heterogeneous density (malignant) were observed.
- Specific CT signs for liposarcoma (fat density) and neural tumors (paraspinal location, dumbbell shape) were noted.
- Tumor encasement of vessels, invasion of adjacent structures, multiple masses, and pelvic invasion indicated non-resectability.
Conclusions:
- CT provides valuable information for characterizing retroperitoneal neoplasms.
- While differentiation is challenging, specific CT features can suggest tumor type and malignancy.
- Post-operative follow-up CT every 6 months for 2 years is recommended for early recurrence detection.
Related Concept Videos
Computed Tomography
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Positron Emission Tomography
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body being...
Imaging Studies II: Positron Emission Tomography and Scintigraphy
Fundamental Principles of PET
Imaging Studies III: Computed Tomography
Imaging Studies IV: Magnetic Resonance Imaging
Imaging Studies V: Intravenous Urography and Retrograde Pyelography

