Related Experiment Videos
[Peripheral nerves injection injury: the clinical and experimental study]
1Institute of Orthopedics and Traumatology, Fourth Military Medical University.
Zhonghua Wai Ke Za Zhi [Chinese Journal of Surgery]
|September 1, 1992
Summary
Peripheral nerve injuries from injections can be effectively managed with early epineurial incision and saline irrigation, showing superiority over neurolysis in experimental studies for emergency treatment.
Area of Science:
- Neurology
- Surgical Pathology
- Experimental Medicine
Context:
- Postinjection injuries to peripheral nerves present a significant clinical challenge.
- Operative management strategies require careful consideration for optimal outcomes.
- Understanding early nerve changes postinjection is crucial for timely intervention.
Purpose:
- To report outcomes of operative management for peripheral nerve postinjection injuries.
- To compare the efficacy of early saline irrigation versus neurolysis in experimental nerve injury models.
- To evaluate neurophysiological, histological, and ultrastructural changes following nerve injury.
Summary:
- Neurolysis yielded good to excellent results in 64.6% of 58 patients with peripheral nerve postinjection injuries.
- Experimental studies on rabbit peroneal nerves indicated that intrafascicular injection causes rapid, severe injury.
- Early epineurial incision with saline irrigation proved superior to neurolysis and is recommended as an emergency procedure.
Impact:
- Highlights the effectiveness of prompt surgical intervention for postinjection nerve injuries.
- Provides evidence supporting saline irrigation as a superior emergency treatment over neurolysis.
- Informs clinical practice regarding the timing and methods for managing iatrogenic nerve damage.