Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Propylthiouracil and peripheral neuropathy.

V Van Boekel1, J M Godoy, L A Lamy

  • 1Hospital de Ipanema (HI), Brasil.

Arquivos De Neuro-Psiquiatria
|June 1, 1992
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A straight choice: avoiding septal re-deviation using titanium plates. A 16 year retrospective patient follow-up evaluation.

Rhinology·2017
Same author

Society for Vascular Surgery and American Venous Forum Guidelines on the management of venous leg ulcers: the point of view of the International Union of Phlebology.

International angiology : a journal of the International Union of Angiology·2015
Same author

Leprosy neuropathy evaluated by NCS is independent of the patient's infectious state.

Clinical neurology and neurosurgery·2015
Same author

210Po concentration in Perna perna mussels: looking for radiation effects.

Journal of environmental radioactivity·2007
Same author

226Ra, 228Ra and 228Th in scale and sludge samples from the Campos Basin oilfield E&P activities.

Radiation protection dosimetry·2002
Same author

Environmental impact studies of barium and radium discharges by produced waters from the "Bacia de Campos" oil-field offshore platforms, Brazil.

Journal of environmental radioactivity·2002

Propylthiouracil can cause peripheral neuropathy, a rare side effect in hyperthyroidism. Neurological symptoms in a Graves' disease patient resolved after discontinuing this medication, suggesting a potential toxic effect.

Area of Science:

  • Neurology
  • Endocrinology
  • Pharmacology

Background:

  • Hyperthyroidism, particularly Graves' disease, can present with various neurological complications.
  • Peripheral neuropathy is an uncommon manifestation of hyperthyroidism.

Observation:

  • A 38-year-old female with Graves' disease developed peripheral neuropathy during treatment.
  • The patient was receiving propylthiouracil for her hyperthyroid condition.

Findings:

  • Neurological signs and symptoms of peripheral neuropathy improved significantly after propylthiouracil dosage was reduced.
  • Complete resolution of neurological manifestations was observed upon drug discontinuation.

Implications:

  • This case highlights a potential neurotoxic effect of propylthiouracil on the peripheral nervous system.

Related Experiment Videos

  • Clinicians should consider propylthiouracil-induced peripheral neuropathy in hyperthyroid patients presenting with neurological deficits.
  • Further investigation into the mechanism of propylthiouracil neurotoxicity is warranted.