Related Experiment Videos
[Left ventricular volume decrease during isovolumic relaxation period in gated blood pool scintigraphy: observations
T Furuta1, K Kodera, H Tabuchi
1Second Department of Internal Medicine, Kagoshima University School of Medicine.
Journal of Cardiology
|January 1, 1992
Summary
In patients with old myocardial infarction (OMI), a specific left ventricular (LV) volume decrease during isovolumetric relaxation was linked to asynchronous LV relaxation. This finding aids in understanding OMI complications.
Area of Science:
- Cardiology
- Nuclear Medicine
- Cardiovascular Imaging
Background:
- Old myocardial infarction (OMI) can lead to complex left ventricular (LV) dysfunction.
- Gated blood pool scintigraphy (GBPS) is used to assess LV volume dynamics.
Purpose of the Study:
- To investigate the mechanism and clinical significance of LV volume decrease during isovolumetric relaxation in OMI patients.
- To correlate this phenomenon with wall motion abnormalities and abnormal diastolic flow.
Main Methods:
- Studied 113 OMI patients using GBPS, left ventriculography, and Doppler echocardiography.
- Analyzed time-activity curves from GBPS for LV volume changes during isovolumetric relaxation.
- Compared patients with (Group I) and without (Group II) the observed phenomenon.
Main Results:
- The LV volume decrease phenomenon was observed in 25% of anterior OMI patients.
- Group I showed significantly more dyskinetic/aneurysmal anterior/apical wall motion (85% vs. 39%) on ventriculography.
- Abnormal reversed LV flow during isovolumetric relaxation was more frequent in Group I (54% vs. 8%) via Doppler echocardiography.
Conclusions:
- The observed LV volume decrease is likely due to asynchronous LV relaxation.
- This phenomenon is a potential indicator of asynchronous relaxation in OMI patients.