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[Wilms' tumors, 12 case reports].

H R Chacar1, N Asmar, R Bou-Saba

  • 1Faculté de Médecine de l'Université Saint-Joseph, Beyrouth, Liban.

Le Journal Medical Libanais. the Lebanese Medical Journal
|January 1, 1992
PubMed
Summary
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Wilms tumor treatment is highly successful in pediatric oncology. This study of 12 nephroblastoma cases confirms good outcomes, especially for early-stage Wilms tumor.

Area of Science:

  • Pediatric Oncology
  • Nephrology

Context:

  • Wilms tumor (nephroblastoma) is a significant malignancy in children.
  • Historically, treatment outcomes for Wilms tumor have varied.
  • This study reviews a cohort of pediatric nephroblastoma cases.

Purpose:

  • To evaluate the treatment outcomes of Wilms tumor in a series of pediatric cases.
  • To analyze the presenting signs and diagnostic methods for Wilms tumor.
  • To correlate tumor stage with prognosis in pediatric nephroblastoma.

Summary:

  • The study analyzed 12 cases of nephroblastoma treated between 1979 and 1987.
  • The most common presenting sign was a large abdominal mass (75%), with intravenous pyelogram (IVP) confirming diagnosis in 90% of cases.
  • Five patients in Stage I achieved remission, while advanced stages (II-V) indicated a poor prognosis.

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Impact:

  • Confirms the high success rate of Wilms tumor treatment in pediatric oncology.
  • Highlights the importance of early diagnosis and staging for improved patient outcomes.
  • Provides data supporting current treatment protocols and identifies areas for future research in Wilms tumor management.