[Intracerebral hemorrhage in a female patient with pulmonary sarcoidosis]

Sarcoidosis is a chronic, multisystem disorder of unknown cause which is characterized by the accumulation of lymphocytes and mononuclear phagocytes in non-caseating epitheloid granulomas in affected organs. Sarcoidosis is now thought to be a disease of abnormal immune regulation, probably because of an exaggerated helper T lymphocyte process. The presence of immunoglobulins and complement in sarcoid granulomata suggests that the humoral mechanism may also be important. Signs of neurosarcoidosis are observed in only 5% of patients with equal involvement of the peripheral and central nervous system. A rare case of sarcoidosis with typical pulmonary dysfunction, chronic polyneuropathy of asymmetric type and intracerebral bilateral occipital hemorrhage who recovered dramatically within two months after corticosteroid therapy, is reported. Intracerebral haemorrhage as a complication of sarcoidosis has, to our knowledge, not been previously reported.