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[Helicobacter pylori in Barrett esophagus]
1Servicio de Patología, Hospital de Gastroenterología Dr. Bonorino Udaondo, Capital Federal, Argentina.
Acta Gastroenterologica Latinoamericana
|January 1, 1992
Summary
Helicobacter Pylori colonization was found in 23.8% of adults with Barrett's esophagus, particularly in those over 50. This finding warrants further long-term studies in larger patient groups.
Area of Science:
- Gastroenterology
- Microbiology
Background:
- Barrett's esophagus is a risk factor for esophageal adenocarcinoma.
- The role of Helicobacter Pylori in Barrett's esophagus is not fully understood.
Purpose of the Study:
- To determine the prevalence of Helicobacter Pylori colonization in adult patients with Barrett's esophagus.
- To investigate the association between Helicobacter Pylori and specific Barrett's esophagus histological features.
Main Methods:
- A cohort of 21 adult patients with Barrett's esophagus underwent evaluation for Helicobacter Pylori.
- Esophageal biopsies were analyzed for the presence of Helicobacter Pylori.
Main Results:
- Helicobacter Pylori was detected in 23.8% of patients with Barrett's esophagus.
- The prevalence was higher (26.6%) in patients over 50 years old.
- In positive cases, Barrett's esophagus showed fundic gastric mucosa without intestinal metaplasia. Helicobacter Pylori was absent in patients with reflux esophagitis without Barrett's esophagus.
Conclusions:
- Helicobacter Pylori colonization occurs in a subset of patients with Barrett's esophagus.
- Further research with larger cohorts and long-term follow-up is needed to clarify the clinical significance and long-term implications of this association.