Related Experiment Videos
Combination therapy with cisplatin: modulation of activity and tumour sensitivity
H J Guchelaar1, D R Uges, E G de Vries
1Department of Pharmacy and Toxicology, University Hospital, Groningen, The Netherlands.
Clinical Oncology (Royal College of Radiologists (Great Britain))
|November 1, 1992
Abstract:
Although cisplatin is applied with success in clinical oncology, this success is limited because some cancers are initially unresponsive to cisplatin or become so during treatment. In this review, some strategies to overcome this problem are discussed. Among these are combination with the differentiation inducing agent, retinoic acid, combination with radiotherapy, and the use of hyperthermia.