Reduction of risk factors for osteoporosis among adolescents and young adults
Abstract:
Osteoporosis is the most common of all skeletal disorders. The most commonly accepted definition of osteoporosis is a decrease in the amount of calcified bone tissue to the point that fractures occur with minimal trauma. Researchers have shown that peak bone mass at skeletal maturity may be the single most important factor in the development of osteoporosis. At present, no satisfactory way to replace lost bone exists, and the ideal treatment for osteoporosis is prevention, which must begin early in life. The most promising approach in the primary prevention of osteoporosis is to help each person achieve as high a peak skeletal mass and bone density as genetically possible prior to skeletal maturity. Furthermore, identifying those adolescents and young adults at risk is of clinical value for prediction and counseling purposes. Recommendations for achieving the maximal bone mass prior to skeletal maturity, as well as methods of assessing and minimizing the risk factors for osteoporosis, will be discussed.
Related Concept Videos
Bone Remodeling
Osteoclasts in Bone Remodeling
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Hormones and Bone Tissue
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
Role of Vitamins in Maintaining Bone Health
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Urinary Tract Calculi IV: Nutrition Therapy and Prevention

