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Updated: Jul 19, 2026

Modeling Colitis-Associated Cancer with Azoxymethane (AOM) and Dextran Sulfate Sodium (DSS)
Published on: September 11, 2012
[Ulcerative colitis and cancer]
1Servicio de Cirugía, Hospital Municipal L. Lucero, Buenos Aires, República Argentina.
Abstract:
We present two cases of ulcerative colitis complicated with rectum carcinoma, after ten years of the beginning of the illness. The author present 50 cases of ulcerative colitis treated in Bahía Blanca, Buenos Aires, Argentina between 1958 and 1986. In two of these cases we found the cancer localized in rectum (4%). The first was a 62 years old man, to have had a good post operative evolution with Miles operation. The second was a 56 years old woman who had a bad evolution with proctocolectomy and ileostomy, surviving 4 years with multiple metastasis. We recommend to perform an efficient control of the patients with more than ten years of evolution of the disease with colonoscopy and biopsies of mucosal of the colon and rectum, and C.E.A. echography, etc. We think that the technique of ileoanal-anastomosis with ileal reservoir is the best current method for the treatment of the cases of ulcerative colitis and cancer.
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