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[The use of acetylsalicylic acid as a platelet antiaggregant]
A R de Araújo1, M I Sobreira, G O de Melo
1Fundação de Hematologia e Hemoterapia de PE, Hospital das Clínicas, UFPE.
Purpose:
To comprove the efficiency of acetyl salicylic acid (ASA) as platelet antiaggregant drug, a 100 mg/day dose base.
Methods:
Two hundred and fifty-eight patients were studied between 1988 and 1990. Platelet functions were measured using an aggregometer plus ADP 5 as platelet aggregation inductor.
Results:
Two groups were studied: 1st group, using ASA (111 patients), 91 hypoaggregants; 2nd group, not using ASA (147 patients), 120 normals, 12 hypoaggregants and 15 hyperaggregants. From the 2nd group, 91 had another evaluation under the use of ASA and showed a clear effect of the drug.
Conclusion:
The use of aspirin, 100 mg/day dose, is enough to reduce platelet antiaggregation.