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[Fetal atrioventricular block].

L M Lopes1, S C Cha, L Sadek

  • 1Departamento de Obstetrícia e Ginecologia, Hospital das Clínicas, FMUSP.

Arquivos Brasileiros De Cardiologia
|October 1, 1992
PubMed
Summary
This summary is machine-generated.

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Maternal anti-RO antibodies are linked to isolated fetal complete heart block. However, fetuses with heart block and complex cardiac malformations have a poor prognosis.

Area of Science:

  • Cardiology
  • Maternal-Fetal Medicine
  • Pediatric Cardiology

Context:

  • Congenital heart block (CHB) is a rare but serious condition.
  • Fetal hydrops, bradycardia, and cardiac malformations are key indicators for CHB referral.
  • Routine ultrasound screening identifies suspected CHB cases.

Purpose:

  • To investigate the pathogenesis, evolution, and prognosis of fetal complete heart block.
  • To correlate maternal anti-RO antibodies with isolated CHB.
  • To assess outcomes for fetuses with CHB and complex cardiac anomalies.

Summary:

  • Echocardiography was performed on 600 fetuses with suspected CHB.
  • Isolated CHB was identified in 6 fetuses; 5 were complete.
  • CHB associated with complex cardiac disease had no survivors.

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Impact:

  • Confirms the association between maternal anti-RO antibodies and isolated fetal CHB.
  • Highlights the poor prognosis of CHB in fetuses with complex cardiac malformations.
  • Informs clinical management and counseling for CHB.