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Published on: July 29, 2014
Analgesic activity of dipipanone hydrochloride in student volunteers
British Journal of Pharmacology and Chemotherapy
|March 1, 1957
Abstract:
Dipipanone hydrochloride raised the threshold to ischaemic pain in healthy human volunteers. The lowest dose producing a significant rise in pain threshold was 10.0 mg. The peak effect for all doses was reached after about 2 hr. Side effects, the most common of which were drowsiness, nausea, and vertigo, are described and analysed. The drug was shown to be a histamine liberator and to cause pain and tenderness at injection sites.
Keywords:
METHADON/related compounds
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