Homologous immunological studies of ocular lens. I. In vitro observations

Five lens antigens of rabbits can induce antibodies homologously as evidenced by agar precipitin technics. Cross-reactions of lenses of other species (organ specificity) may be due to similarity of varying numbers of these antigens. Newborn and 26-day embryo rabbit lenses seem to have decreased concentrations of, or lack, one antigen present in adult rabbit lens. Streptolysin "O" concentrates appear to act as an adjuvant for homologous lens immunization in rabbits.