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Published on: March 30, 2014
[Pediatric AIDS: a report of the first fatal Cuban pediatric case]
I González Núñez1, V Capó de Paz, M E Rodríguez Barreras
1Instituto de Medicina Tropical Pedro Kourí.
Insights
This case report details a Cuban child with acquired immunodeficiency syndrome (AIDS) from perinatal transmission. The child experienced severe symptoms including opportunistic infections and neurological complications, leading to death.
Area of Science:
- Pediatrics
- Infectious Diseases
- Virology
Background:
- Perinatal transmission of Human Immunodeficiency Virus (HIV) is a significant concern in pediatric populations.
- Early diagnosis and management are crucial for improving outcomes in vertically infected infants.
Observation:
- A case of a Cuban child diagnosed with AIDS following perinatal HIV transmission is presented.
- The child exhibited failure to thrive, recurrent respiratory infections (including Pneumocystis carinii pneumonia), oral candidiasis, cryptosporidiosis, and intestinal amebiasis.
Findings:
- The infant presented with severe opportunistic infections and developmental delay shortly after birth.
- Autopsy revealed the cause of death as endocranial hypertension secondary to non-specific sub-acute viral meningitis.
Implications:
- This case highlights the severe clinical manifestations and challenges in managing pediatric AIDS acquired perinatally.
- It underscores the importance of early detection and intervention strategies for HIV-infected infants to prevent severe morbidity and mortality.
Abstract:
The case of a Cuban child with AIDS acquired by perinatal transmission is reported. Thirteen days after birth, the child had chronic diarrhoeas affecting its pondostatural development. It was hospitalized many times due to recurrent respiratory processes, in one of which Pneumocystis carinii was detected. Oral candidiasis, cryptosporidiosis and intestinal amebiasis in faeces were also diagnosed. It died with generalized tonic-clonic convulsions and bradypnea. At autopsy, the direct death cause was endocranial hypertension due to unspecific sub-acute viral meningitis.
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