Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Chronic hiccups].

J Cabane1, V Desmet, J P Derenne

  • 1Service de Médecine Interne (Pr J. C. IMBERT), Hôpital Saint-Antoine, Paris.

La Revue De Medecine Interne
|November 1, 1992
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Effects of HD-tDCS stimulation on apathy, depression and their speech parameters].

L'Encephale·2021
Same author

[Diagnostic criteria for obstructive sleep apnea syndrome in adolescent].

Revue des maladies respiratoires·2021
Same author

[Telemonitoring in continuous positive airway pressure-treated patients with obstructive sleep apnoea syndrome: An algorithm proposal].

Revue des maladies respiratoires·2020
Same author

[Diagnostic journey of type 1 Gaucher Disease patients: A survey including internists and hematologists].

La Revue de medecine interne·2019
Same author

The Clinical Relevance of Antifibrillarin (anti-U3-RNP) Autoantibodies in Systemic Sclerosis.

Scandinavian journal of immunology·2016
Same author

[Periungueal capillaroscopy: an easy and reliable method to evaluate all microcirculation diseases].

La Revue de medecine interne·2015
Same journal

[Atypical low back pain].

La Revue de medecine interne·2026
Same journal

[Polycythemia associated chronic haemolysis].

La Revue de medecine interne·2026
Same journal

[Persistent headaches in a 55 year-old man].

La Revue de medecine interne·2026
Same journal

[Abdominal pain, fever and arthralgia in a 49-year-old woman].

La Revue de medecine interne·2026
Same journal

[Cardiorespiratory functional disorders: A transnosologic approach].

La Revue de medecine interne·2026
Same journal

[Diagnostic evaluation for suspected polycythemia].

La Revue de medecine interne·2026
See all related articles

Reflux esophagitis is the most common cause of chronic hiccups in adults. Hiccups can create a cycle with esophageal issues, making treatment challenging, though baclofen shows some promise.

Area of Science:

  • Gastroenterology
  • Neurology

Background:

  • Chronic hiccups, defined as lasting over 48 hours, present a diagnostic and therapeutic challenge in adults.
  • Investigating the underlying causes and effective treatments for persistent hiccups is crucial for patient management.

Observation:

  • Reflux esophagitis was identified as the most frequent cause, accounting for 50% of the 18 reported adult cases.
  • A potential vicious cycle where hiccups induce esophageal dyskinesia, leading to gastroesophageal reflux, was observed.

Findings:

  • Treatment primarily focused on addressing the root cause, but hiccups often persisted even after successful intervention for conditions like reflux esophagitis.
  • Central nervous system depressants and muscle relaxants showed limited efficacy, with baclofen demonstrating a 60% initial response rate.

Related Experiment Videos

Implications:

  • Understanding the complex interplay between hiccups and gastroesophageal reflux is essential for developing targeted therapies.
  • Baclofen emerges as a potentially effective pharmacological option for managing intractable chronic hiccups, warranting further investigation.