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Premature menarche--a legend or a defined clinical syndrome
J Zarzycki1, A Pawlikowska-Haddal, M Hilczer
1Department of Pediatric Endocrinology, Institute of Endocrinology, Medical Academy of Lódź.
Endokrynologia Polska
|January 1, 1992
Abstract:
The properness of diagnosing the premature menarche as isolated clinical syndrome is often questioned. A long-term observation od 2 girls with premature menarche has been described. A discussion is presented about the role of imbalance within the hypothalamus-pituitary-gonads axis and the role of disturbances in peripheral responsiveness to sex hormones in the patho-mechanism of premature menarche.