[Computerized planning of radiotherapy]

Area of Science:

• Radiology
• Endocrinology
• Neuroimaging

Context:

• The hypothalamohypophyseal system is complex, with various diseases affecting pituitary function.
• Accurate diagnosis and monitoring of pituitary disorders are crucial for effective patient management.
• Magnetic resonance tomography (MRT) offers detailed visualization of the pituitary gland and surrounding structures.

Purpose:

• To evaluate the utility of MRT in diagnosing prevalent hypothalamohypophyseal system diseases.
• To establish diagnostic criteria for hypophyseal macroadenoma and 'empty' sella turcica using MRT.
• To assess the role of MRT in monitoring pituitary status during therapeutic interventions.

Summary:

• MRT was performed on 148 patients with hypothalamohypophyseal diseases and 13 with primary hypothyrosis.
• Findings revealed diverse MRT presentations, enabling reliable diagnosis of pituitary macroadenoma and 'empty' sella.
• The study suggests qualitative and quantitative MRT criteria for these conditions and highlights MRT's role in dynamic follow-up during therapy.

Impact:

• MRT is a valuable tool for diagnosing pituitary macroadenoma and 'empty' sella.
• The study provides criteria for MRT diagnosis, aiding clinical decision-making.
• MRT facilitates monitoring treatment efficacy and observing therapeutic effects on pituitary morphology, such as 'empty' sella formation.