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Parvovirus B19 outbreak in a children's ward
1Division of Communicable Diseases, Royal Free Hospital and School of Medicine, London, UK.
Lancet (London, England)
|January 11, 1992
Summary
Parvovirus B19 outbreaks pose risks to vulnerable populations. During a hospital outbreak, infection control measures were implemented, but their effectiveness in limiting spread remains uncertain.
Area of Science:
- Virology
- Infectious Diseases
- Hospital Epidemiology
Background:
- Parvovirus B19 infection presents significant risks for pregnant women, individuals with hemolytic anemia, and the immunocompromised.
- Managing hospital outbreaks requires balancing patient protection with maintaining essential medical services.
Purpose of the Study:
- To investigate a Parvovirus B19 outbreak in a pediatric ward.
- To assess the infection control measures implemented during the outbreak.
Main Methods:
- Screening of 58 hospital staff members for Parvovirus B19 markers (serum IgM and viraemia).
- Assessment of infection development in susceptible staff and immunocompromised patients.
- Implementation of isolation, immunoglobulin therapy, and ward restrictions.
Main Results:
- 4 of 6 susceptible male staff and 6 of 24 susceptible female staff became infected (p=0.05).
- 1 of 11 infected adults and 2 of 12 immunocompromised patients remained asymptomatic.
- No clear correlation between implemented measures and infection spread limitation was established.
Conclusions:
- Parvovirus B19 can spread asymptomatically in hospital settings.
- The effectiveness of specific infection control interventions during this outbreak could not be definitively determined.
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