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Nucleoside triphosphate levels in Streptomyces hydrogenans during growth and induction of 20beta-hydroxysteroid
Abstract:
Levels of the purine nucleoside triphosphates are decreasing towards the end of log phase growth of Streptomyces hydrogenans. Induction of 20beta-hydroxysteroid dehydrogenase by addition of 11beta,21-dihydroxy-4,17(20)-pregnadien-3-one to the growth medium leads to a pronounced drop in purine nucleoside triphosphate levels with is irreversible in contrast to the initial loss and later accumulation of RNA.