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Synthesis and binding of peptide T and aminoacyl derivatives to CD4+ lymphocytes
L H van den Heever1, J H Jordaan, I A Dubery
1Department of Biochemistry, Delta G Scientific, Johannesburg, South Africa.
The International Journal of Biochemistry
|February 1, 1992
Abstract:
1. Peptide T and four other aminoacyl derivatives of this octapeptide were synthesized on solid phase support using the Boc and Fmoc procedures. 2. The octapeptides were modified by chloroacetylation and radiolabelled by halogen exchange with 125I. 3. Purified and crude extracts of lymphocytes were used to determine the binding of the octapeptides at different concentrations.