Related Experiment Video
Updated: Aug 7, 2026
Loss-of-Function Approach in the Embryonic Chick Retina by Using Tol2 Transposon-Mediated Transgenic Expression of Artificial microRNAs
Published on: May 18, 2022
Taurine uptake into chick B cells
1Division of Animal and Veterinary Sciences, College of Agriculture and Forestry, West Virginia University, Morgantown 26506.
Abstract:
The objective of the present study was to determine whether chick B cells possess a specific transport system for taurine. The Bursa of Fabricius was isolated from newly hatched to 6-week-old chicks and an enriched fraction (86.2%) of B cells was isolated. The chick B cells maintained a high intracellular taurine concentration (0.8-1.12 mM) that decreased with age. The B cells exhibited carrier-mediated and simple diffusion uptake components, but only the carrier-mediated component increased with age. Inhibitor studies indicated taurine uptake was sodium and energy dependent. The data demonstrate that chick B cells possess a specialized taurine transport system and the activity of this system changes during posthatch B cell development.
