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[Primary hypothyroidism in normal thyroid gland morphology]
1Medizinische Kernklinik und Poliklinik, Univ.-Krankenhaus Eppendorf, Hamburg.
Abstract:
A 25 year old patient developed hypothyroidism with antibodies against thyroglobulin, thyroid microsomes and thyrotropin receptors. Thyroid 99m-technetium-uptake was 0%. Ultrasound investigation revealed a normal sized, homogenous thyroid gland. Histology showed lymphocyte infiltration but regular follicles. These results suggest the cause of hypothyroidism to be thyrotropin inhibiting immunoglobulins with no parenchyma-destroying properties.