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[Studies on the excretion of urinary glycylprolyl dipeptidyl-aminopeptidase (GP-DAP) during normal pregnancy]
Y Negishi1, H Shibuya-Saruta, M Sugiyama
1Department of Obstetrics and Gynecology, Tokyo Medical College.
Rinsho Byori. the Japanese Journal of Clinical Pathology
|February 1, 1992
Abstract:
Several investigators reported that GP-DAP activity, one of dipeptidyl-aminopeptidases, increased in urine of patients with various renal diseases. In this study, we determined urinary GP-DAP and NAG activities of 165 subjects in normal pregnant women. It was clear that urinary GP-DAP was increased less than NAG with the progress of normal pregnancy. In conclusion, it is suggested that urinary GP-DAP may be a better marker than NAG for the discrimination of renal diseases from normal pregnancy.