Related Experiment Video
Updated: Jun 18, 2026

Eye Tracking, Cortisol, and a Sleep vs. Wake Consolidation Delay: Combining Methods to Uncover an Interactive Effect of Sleep and Cortisol on Memory
Published on: June 18, 2014
Physiological effects of emotion: assessment via hypnosis
P J Whorwell1, L A Houghton, E E Taylor
1Department of Medicine, University Hospital of South Manchester, UK.
Hypnosis significantly reduced colonic motility and physiological stress markers in irritable bowel syndrome patients. Specific emotions like anger and excitement increased colonic activity, while happiness further decreased it.
Area of Science:
- Gastroenterology
- Psychophysiology
- Neurogastroenterology
Background:
- Assessing physiological stress effects requires suitable laboratory techniques.
- Hypnosis offers a safe method to induce intense emotional states for research.
Purpose of the Study:
- To investigate the impact of hypnotically induced emotions on distal colonic motility in irritable bowel syndrome (IBS) patients.
- To explore hypnosis as a tool for studying emotion-physiology interactions.
Main Methods:
- 18 IBS patients (aged 20-48) underwent hypnosis to induce excitement, anger, and happiness.
- Distal colonic motility, pulse rate, and respiration rate were measured.
- Changes in motility were analyzed based on contraction rate and amplitude.
Main Results:
- Hypnosis alone reduced colonic motility index, pulse, and respiration rates.
- Anger and excitement significantly increased colonic motility, pulse, and respiration.
- Happiness further reduced colonic motility, though not significantly compared to hypnosis alone.
Conclusions:
- Hypnosis is a valuable tool for investigating emotion's physiological effects, potentially beyond the gastrointestinal system.
- Reduced fasting colonic motility under hypnosis may explain its therapeutic benefits for functional bowel disorders.
Related Concept Videos
Sedatives and Hypnotics: Overview
Sedative-hypnotics are categorized into barbiturates, benzodiazepines (BZDs), and non-benzodiazepines or Z-drugs. These drugs work by suppressing central nervous system activity, and this suppression is dose-dependent. Older sedative medications, like barbiturates, follow a linear curve in...
Sedatives and Hypnotics Drugs: Miscellaneous Agents
Melatonin congeners like ramelteon (Rozerem) and tasimelteon (Hetlioz) selectively bind to melatonin receptors (MT1 and MT2) and thus mimic the actions of melatonin, a hormone that regulates sleep-wake cycles. Tasimelteon is primarily used for non-24-hour sleep-wake disorder, common in blind patients. They are also used to treat conditions like insomnia...
Understanding Sleep
The circadian rhythm, a nearly 24-hour cycle, is deeply influenced by environmental light cues. Light exposure directly affects the hypothalamus, which in turn regulates...
Nightmares and Night Terrors
Nightmares often...
Substance Use Disorders Affecting Sleep
Understanding the concepts of physical dependence,...
The Influence of Affect on Cognition

