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Effects of ursodeoxycholic acid on liver function in patients with cystic fibrosis and chronic cholestasis
C Galabert1, J C Montet, D Lengrand
1Laboratoire de Biochimie, Hôpital Renée Sabran (Hopitaux de Lyon), Giens, Hyères, France.
The Journal of Pediatrics
|July 1, 1992
Abstract:
Ursodeoxycholic acid, 10 to 20 mg/kg per day, was administered for 1 year to 22 patients with cystic fibrosis and chronic cholestasis, resulting in significantly improved liver enzyme values. However, evidence of cholestasis continued, as shown by the pattern of alkaline phosphatase isoenzymes.