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[Diagnostic value of blood fibrinogen in leptospirosis]

Revista De Igiena, Bacteriologie, Virusologie, Parazitologie, Epidemiologie, Pneumoftiziologie. Bacteriologia, Virusologia, Parazitologia, Epidemiologia
|July 1, 1976
PubMed

Insights

Fibrinogenemia testing is valuable for diagnosing early leptospirosis, especially in atypical cases. This method proves more indicative than erythrocyte sedimentation rate in the initial disease stages.

Area of Science:

  • Infectious Diseases
  • Hematology

Context:

  • Leptospirosis presents with uncharacteristic forms, complicating early diagnosis.
  • Accurate diagnosis in the initial eight days is crucial for effective management.

Purpose:

  • To evaluate the diagnostic utility of presumptive fibrinogenemia testing.
  • To compare fibrinogenemia determination with erythrocyte sedimentation rate in early leptospirosis.

Summary:

  • A study involving 42 cases of leptospirosis assessed fibrinogenemia during the first eight days of illness.
  • Fibrinogenemia determinations showed higher diagnostic suggestiveness in the early disease phase compared to erythrocyte sedimentation rate.

Impact:

  • Highlights fibrinogenemia as a potentially superior early diagnostic marker for leptospirosis.
  • Informs clinical practice regarding diagnostic approaches for atypical leptospirosis presentations.

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