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In utero transplantation of stem cells in humans: technical aspects and clinical experience during pregnancy
D Raudrant1, J L Touraine, A Rebaud
1Department of Gynecology and Obstetrics A, Hôpital de l'Hôtel-Dieu, Lyon, France.
Bone Marrow Transplantation
|January 1, 1992
Abstract:
Four fetal patients have received fetal liver cell transplants in utero, at the fertilization ages of 12-28 weeks. Depending on the age, intraperitoneal injection or intravenous infusion into the umbilical vein was used, under ultrasonic guidance. In three of the four cases, engraftment has been obtained and has resulted in cure or significant improvement of the inherited disease.