GABA and glutamate receptors as therapeutic targets in neurodegenerative disorders

The orthosteric GABAA receptor ligand Thio-4-PIOL displays distinctly different functional properties at synaptic and extrasynaptic receptors.

British journal of pharmacology·2013

Lack of a high affinity uptake system for the GABA agonists THIP and isoguvacine in neurons and astrocytes cultured from mouse brain.

Neurochemistry international·2010

Characterization of the uptake of GABA, nipecotic acid and cis-4-OH-nipecotic acid in cultured neurons and astrocytes.

Neurochemistry international·2010

Modification of the philanthotoxin-343 polyamine moiety results in different structure-activity profiles at muscle nicotinic ACh, NMDA and AMPA receptors.

Neuropharmacology·2003

Recent advances in the medicinal chemistry of polyamine toxins.

Mini reviews in medicinal chemistry·2002

Resolution, configurational assignment, and enantiopharmacology at glutamate receptors of 2-amino-3-(3-carboxy-5-methyl-4-isoxazolyl)propionic acid (ACPA) and demethyl-ACPA.

Chirality·2001

Spontaneous reversal of p-glycoprotein expression in multidrug resistant cell lines.

Pharmacology & toxicology·2003

Melatonin protects against mercury(II)-induced oxidative tissue damage in rats.

Pharmacology & toxicology·2003

Inhibition by uric acid of free radicals that damage biological molecules.

Pharmacology & toxicology·2003

In vitro induction of differentiation by ginsenoside Rh2 in SMMC-7721 hepatocarcinoma cell line.

Pharmacology & toxicology·2003

Mepivacaine alters vascular responsiveness to vasoconstrictors in aortic rings from normal and aortic-banded rats.

Pharmacology & toxicology·2003

6-Ethyl-N,N'-bis(3-hydroxyphenyl)[1,3,5]triazine-2,4-diamine (RS-0466) enhances the protective effect of brain-derived neurotrophic factor on amyloid beta-induced cytotoxicity in cortical neurones.

Pharmacology & toxicology·2003

The Gut-Brain Axis and Neurodegenerative Diseases: From Mechanistic Pathways to Therapeutic Interventions.

Probiotics and antimicrobial proteins·2026

Balance control is more affected in older than younger adults by repeated visual perturbations during walking.

GeroScience·2026

Tremor or myoclonus? A practical clinical approach to distinguishing two common hyperkinetic movement disorders.

Revue neurologique·2026

Ganoderma lucidum polysaccharides alleviate cognitive impairment in sleep-deprived mice: Association with gut microbiota remodeling.

Food research international (Ottawa, Ont.)·2026

The Evaluation of Clinical and Dermatoscopic Features of Scalp Nevi in Adults.

Dermatology practical & conceptual·2026

Fifteen-year surveillance of non-typhoidal Salmonella bloodstream infections in a tertiary care hospital in southern Türkiye.

Journal of infection in developing countries·2026

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GABA and glutamate receptors as therapeutic targets in neurodegenerative disorders

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The orthosteric GABAA receptor ligand Thio-4-PIOL displays distinctly different functional properties at synaptic and extrasynaptic receptors.

Lack of a high affinity uptake system for the GABA agonists THIP and isoguvacine in neurons and astrocytes cultured from mouse brain.

Characterization of the uptake of GABA, nipecotic acid and cis-4-OH-nipecotic acid in cultured neurons and astrocytes.

Modification of the philanthotoxin-343 polyamine moiety results in different structure-activity profiles at muscle nicotinic ACh, NMDA and AMPA receptors.

Recent advances in the medicinal chemistry of polyamine toxins.

Resolution, configurational assignment, and enantiopharmacology at glutamate receptors of 2-amino-3-(3-carboxy-5-methyl-4-isoxazolyl)propionic acid (ACPA) and demethyl-ACPA.

Spontaneous reversal of p-glycoprotein expression in multidrug resistant cell lines.

Melatonin protects against mercury(II)-induced oxidative tissue damage in rats.

Inhibition by uric acid of free radicals that damage biological molecules.

In vitro induction of differentiation by ginsenoside Rh2 in SMMC-7721 hepatocarcinoma cell line.

Mepivacaine alters vascular responsiveness to vasoconstrictors in aortic rings from normal and aortic-banded rats.

6-Ethyl-N,N'-bis(3-hydroxyphenyl)[1,3,5]triazine-2,4-diamine (RS-0466) enhances the protective effect of brain-derived neurotrophic factor on amyloid beta-induced cytotoxicity in cortical neurones.

The Gut-Brain Axis and Neurodegenerative Diseases: From Mechanistic Pathways to Therapeutic Interventions.

Balance control is more affected in older than younger adults by repeated visual perturbations during walking.

Tremor or myoclonus? A practical clinical approach to distinguishing two common hyperkinetic movement disorders.

Ganoderma lucidum polysaccharides alleviate cognitive impairment in sleep-deprived mice: Association with gut microbiota remodeling.

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Fifteen-year surveillance of non-typhoidal Salmonella bloodstream infections in a tertiary care hospital in southern Türkiye.

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