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Autonomic basis for hypoxia-induced hyperglycaemia in toads (Bufo paracnemis)
E de Castro-e-Silva1, L G Branco, M L Glass
1Departamento de Fisiologia, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Brazil.
Abstract:
1. Toads were exposed to steady hypoxic conditions (inspired PO2 = 40 mmHg) for 60 min. 2. Within the exposure time, glucose concentrations rose from about 30 mg% to a steady level of 45 mg%. The development of hyperglycaemia reached a stable level within 40 min. 3. This effect was eliminated by treatment with either propranolol or atropine, suggesting combined cholinergic and adrenergic activation.