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Serum cholesterol, triglycerides, and aggression in the general population
F G Fowkes1, G C Leng, P T Donnan
1Wolfson Unit for Prevention of Peripheral Vascular Diseases, Department of Public Health Sciences, University of Edinburgh, UK.
Lancet (London, England)
|October 24, 1992
Summary
Low serum triglyceride levels, not cholesterol, were linked to aggression and domineering attitudes in older adults. This finding suggests further research into triglycerides and aggressive behavior is warranted.
Area of Science:
- Cardiovascular Health
- Behavioral Science
- Epidemiology
Background:
- Coronary prevention trials have observed an unexpected rise in violent deaths and suicides.
- This has raised questions about a potential link between low serum cholesterol and personality traits associated with aggression and suicidal behavior.
Purpose of the Study:
- To investigate the association between serum lipid concentrations and personality characteristics related to aggression and suicidal behavior in the general population.
- To examine if low serum cholesterol is linked to personality traits predisposing to aggressive or suicidal actions.
Main Methods:
- The Edinburgh Artery Study analyzed serum lipid levels and personality traits using the Bedford Foulds Personality Deviance Scales.
- A random sample of 1592 men and women aged 55-74 years from Edinburgh general practices participated.
Main Results:
- Serum cholesterol showed no significant association with aggression in men. In women, it was linked to denigratory attitudes in multivariate analysis.
- Serum triglyceride concentration was significantly associated with hostile acts and domineering attitudes, particularly in men, independent of other risk factors.
- Triglyceride levels in prevention trial participants are higher than in the general population.
Conclusions:
- Serum triglyceride concentration, rather than cholesterol, appears to be associated with aggression and domineering personality traits in older adults.
- The relationship between serum triglyceride levels and aggression warrants further investigation, especially considering higher triglyceride levels in prevention trial participants.
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