Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Nicotinic systems and cognitive function.

E D Levin1

  • 1Department of Psychiatry, Duke University Medical Center, Durham, NC 27710.

Psychopharmacology
|January 1, 1992
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Corrigendum to "Stickler A, Hawkey AB, Gondal A, Natarajan S, Mead M, Levin ED. Embryonic exposures to cadmium and PAHs cause long-term and interacting neurobehavioral effects in zebrafish" [Neurotoxicol Teratol. 2024 Mar-Apr;102:107339. doi: 10.1016/j.ntt.2024.107339. Epub 2024 Mar 6].

Neurotoxicology and teratology·2024
Same author

Corrigendum to "Paternal cannabis extract exposure in rats: Preconception timing effects on neurobehavioral effects in offspring" [Neurotoxicology 81 (2020) 180-188].

Neurotoxicology·2021
Same author

Developmental exposure to a complex PAH mixture causes persistent behavioral effects in naive Fundulus heteroclitus (killifish) but not in a population of PAH-adapted killifish.

Neurotoxicology and teratology·2015
Same author

Developmental exposure to organophosphate flame retardants causes behavioral effects in larval and adult zebrafish.

Neurotoxicology and teratology·2015
Same author

Neurotoxicity of FireMaster 550® in zebrafish (Danio rerio): Chronic developmental and acute adolescent exposures.

Neurotoxicology and teratology·2015
Same author

Long-term behavioral impairment following acute embryonic ethanol exposure in zebrafish.

Neurotoxicology and teratology·2015
Same journal

Effects of repeated treatment with opioids that vary in mu opioid receptor efficacy on pain-depressed locomotor behavior in mice.

Psychopharmacology·2026
Same journal

Cannabidiol in the anterior insular cortex attenuates chronic neuropathic pain and comorbid anxiety- and depression-like behaviors: involvement of CB<sub>1</sub> and 5-HT<sub>1A</sub> receptor signaling.

Psychopharmacology·2026
Same journal

Fentanyl decreases arterial blood oxygen saturation more than furanylfentanyl in mice due to increased apnea.

Psychopharmacology·2026
Same journal

Suicide attempt risk among patients receiving methylphenidate: a retrospective cohort study.

Psychopharmacology·2026
Same journal

Investigating the impact of serotonergic psychedelic drugs, MDMA and ketamine on social cognition in psychiatric disorders: A scoping review.

Psychopharmacology·2026
Same journal

OPRD1 rs4654327 and Outcomes of Extended-Release Naltrexone in Alcohol Use Disorder: An Exploratory Prospective Pharmacogenetic Study.

Psychopharmacology·2026
See all related articles

Nicotine enhances cognitive functions like rapid information processing and memory. Studies suggest nicotine may help treat memory deficits in conditions such as Alzheimer's disease.

Area of Science:

  • Neuroscience
  • Pharmacology

Background:

  • Nicotinic acetylcholine receptors play a crucial role in cognitive functions.
  • Nicotine improves information processing and memory in humans and animals.
  • Nicotinic receptor deficits are observed in Alzheimer's disease patients.

Purpose of the Study:

  • To explore the role of nicotinic acetylcholine receptors in cognitive performance.
  • To investigate the potential therapeutic effects of nicotine on cognitive deficits, particularly in Alzheimer's disease.

Main Methods:

  • Review of existing literature on nicotine and cognitive function.
  • Examination of studies involving nicotine administration in experimental animals.
  • Analysis of preliminary clinical findings on nicotine in Alzheimer's disease patients.

Related Experiment Videos

Main Results:

  • Nicotine administration demonstrably improves rapid information processing in humans.
  • Nicotine enhances learning and memory in animal models.
  • Nicotine has shown promise in mitigating memory impairments associated with aging and brain lesions.
  • Preliminary data suggest nicotine can attenuate cognitive deficits in Alzheimer's disease.

Conclusions:

  • Nicotinic acetylcholine receptors are vital for optimal cognitive function.
  • Nicotine shows therapeutic potential for managing cognitive decline in dementia, including Alzheimer's disease.