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A pattern of acute poisoning in children in urban Zimbabwe: ten years experience
1Department of Pharmacy, University of Zimbabwe Medical School, Avondale, Harare.
Insights
Childhood poisoning in Zimbabwe is largely accidental, with household products and traditional medicines being common culprits. Accidental poisonings were most frequent in children aged 0-5 years, while suicides were noted in older children.
Area of Science:
- Public Health
- Epidemiology
- Toxicology
Background:
- Childhood poisoning is a significant public health concern globally.
- Understanding the epidemiology of poisoning in children is crucial for developing targeted prevention strategies.
- Zimbabwean data on childhood poisoning trends, particularly from the 1980s, provides valuable insights into regional patterns.
Purpose of the Study:
- To analyze the epidemiology of childhood poisoning in Zimbabwe.
- To identify common toxic agents and demographic patterns in pediatric poisoning cases.
- To evaluate mortality rates and contributing factors in child poisoning admissions.
Main Methods:
- Retrospective analysis of hospital admission data for poisoning cases.
- Inclusion of data from six major urban hospitals in Zimbabwe.
- Study period: 10 years (1980-1989), focusing on children aged 0-15 years.
Main Results:
- Children aged 0-15 years accounted for 47.8% of all poisoning admissions (2873 cases).
- The majority of pediatric cases (75.4%) were in the 0-5 age group, with peak incidence between 1-3 years.
- Accidental poisonings predominated (93.2%), with household products (27.2%) and traditional medicines (23%) as leading agents. Mortality was 4.9% (141 deaths).
Conclusions:
- Childhood poisoning in urban Zimbabwe during the 1980s was primarily accidental and affected young children.
- Household products and traditional medicines represent key areas for poisoning prevention efforts.
- While overall mortality was low, suicides in older children and accidental poisonings in younger children contributed to fatalities.
Abstract:
1. A retrospective analysis was performed to evaluate the epidemiology of poisoning in children based on admissions to six of Zimbabwe's main urban hospitals over a 10-year period from 1980 to 1989 inclusive. 2. A total of 2873 cases were children aged between 0-15 years. This constituted 47.8% of poisoning cases from all age groups (6018) recorded during the study period. 3. All of the children (0-15 years) had signs and symptoms of poisoning on admission and, depending on their severity, were admitted to a ward or to an intensive care unit. A total of 4.9% (141) died. Most of those who died were suicide cases among the 11-15 year age group and accidental poisonings among the 0-15 year old group. 4. The under 0-5 age group constituted the majority of cases (75.4%) in the 0-15 age group, and most were between 1 and 3 years old. The 6-10 and 11-15 age groups formed 12.6% and 12% of the cases, respectively. The sex distribution showed that 53.1% were male. 5. Most incidences were accidental (93.2%). Suicides and parasuicides accounted for 1.9% and there were only two homicides. 6. The commonest toxic agents were: household products (27.2%), traditional medicines (23.%), venoms from snake bites and insect stings (16%) and therapeutic agents (12.4%). Of the therapeutic agents the most frequently implicated were antipsychotics 18.9%, analgesics 16.8%, anti-infectives 11.7%, anticonvulsants (8.2%) and benzodiazepines (7.7%).(ABSTRACT TRUNCATED AT 250 WORDS)
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