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Updated: Sep 13, 2026
Basic Research in Plasma Medicine - A Throughput Approach from Liquids to Cells
Published on: November 17, 2017
Plasmanate: a new plasma substitute for pediatric therapy
Insights
Plasmanate, a human serum protein solution, is an ideal plasma expander for pediatric patients. It is safe and effective for treating shock and hypoproteinemia in children.
Area of Science:
- Medicine
- Pediatrics
- Critical Care
Background:
- Plasma expanders are crucial in managing various medical conditions.
- Ideal plasma expanders should be safe, readily available, and effective.
- Human serum protein solutions offer potential advantages as plasma expanders.
Purpose of the Study:
- To evaluate the efficacy and safety of Plasmanate as a plasma expander in pediatric patients.
- To assess Plasmanate's utility in treating acute shock states and hypoproteinemia.
- To compare Plasmanate with other plasma expanders for pediatric use.
Main Methods:
- Clinical demonstration of Plasmanate's efficacy and safety.
- Treatment of 125 infants and children with Plasmanate.
- Comparative analysis with existing plasma expanders.
Main Results:
- Plasmanate demonstrated freedom from infection and absence of antigenic properties.
- The solution was readily available, clear, and stable.
- Clinical efficacy was observed in treating acute shock and correcting hypoproteinemia in pediatric patients.
Conclusions:
- Plasmanate exhibits ideal attributes for a plasma expander.
- It is particularly effective and safe for treating pediatric shock and hypoproteinemia.
- Plasmanate is recommended as the agent of choice for initial shock treatment in pediatrics.
Abstract:
Plasmanate(R), a human-serum protein solution, appears to have all the attributes of an ideal plasma expander. Freedom from infection, immediate availability in a clear, stable solution and the apparent absence of antigenic properties are particularly valuable qualities. The efficacy and safety of Plasmanate was clinically demonstrated in the treatment of 125 infants and children. This solution seems especially effective in the treatment of acute shock states and for the physiologic correction of hypoproteinemia. Comparison with other plasma expanders makes Plasmanate the agent of choice in the initial treatment of shock states in pediatrics.
