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No association between RFLPs at the porphobilinogen deaminase gene and schizophrenia
1Department of Psychological Medicine, University of Wales College of Medicine, Heath Park, Cardiff, UK.
Human Genetics
|September 1, 1992
Abstract:
An association study of restriction fragment length polymorphisms (RFLPs) in the porphobilinogen deaminase (PBGD) gene and schizophrenia was conducted. RFLPs detected by MspI, PstI, ApaLI and BstNI in intron 1 of the gene were studied in 49 patients and 79 controls. There were no significant differences between the groups in allele frequencies, genotype counts or haplotype distribution.