Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Clinically significant coagulase-negative staphylococci: identification and resistance patterns.

K Refsahl1, B M Andersen

  • 1Department of Medical Microbiology, University Hospital, Tromsø, Norway.

The Journal of Hospital Infection
|September 1, 1992
PubMed
Summary

Coagulase-negative staphylococci (CNS) are a significant cause of infection. Methicillin-resistant Staphylococcus epidermidis increased notably, showing resistance to common antibiotics but remaining sensitive to vancomycin and rifampicin.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Visualization of Local Magnetic Moments Emerging from Impurities in Hund's Metal States of FeSe.

Physical review letters·2020
Same author

Knight Shift and Leading Superconducting Instability from Spin Fluctuations in Sr_{2}RuO_{4}.

Physical review letters·2020
Same author

Imaging orbital-selective quasiparticles in the Hund's metal state of FeSe.

Nature materials·2018
Same author

Discovery of orbital-selective Cooper pairing in FeSe.

Science (New York, N.Y.)·2017
Same author

Ferroelectricity in underdoped La-based cuprates.

Scientific reports·2015
Same author

Interpretation of scanning tunneling quasiparticle interference and impurity states in cuprates.

Physical review letters·2015

Area of Science:

  • Microbiology
  • Clinical Infectious Diseases
  • Antimicrobial Resistance

Background:

  • Coagulase-negative staphylococci (CNS) are clinically significant pathogens.
  • Prevalence and antimicrobial resistance patterns of CNS vary geographically and over time.
  • Understanding CNS epidemiology is crucial for effective infection control.

Purpose of the Study:

  • To investigate the prevalence and antimicrobial susceptibility of CNS isolates in northern Norway between 1989-90.
  • To determine the rate of methicillin resistance in CNS, particularly Staphylococcus epidermidis.
  • To assess the trends in methicillin-resistant Staphylococcus epidermidis (MRSE) over a two-year period.

Main Methods:

  • Isolation and identification of CNS from various clinical samples (blood, catheters, wounds, urine) from 131 patients.

Related Experiment Videos

  • Species identification using Gram-positive Identification Card (Vitek) and 'Staph-zym' (Rosco).
  • Antimicrobial susceptibility testing, including methicillin resistance, against a panel of antibiotics.

    • Main Results:

    • Staphylococcus epidermidis was the predominant CNS species (72.3%).
    • Overall methicillin resistance among CNS was 30.5%, with 35.4% of S. epidermidis isolates being methicillin-resistant (MRSE).
    • MRSE strains exhibited multi-drug resistance, except for sulfonamides, and were resistant to all beta-lactams, including imipenem. Methicillin resistance in S. epidermidis increased from 10% in 1987 to 35.4% in 1989-90. All strains remained sensitive to vancomycin and rifampicin.

    Conclusions:

    • Methicillin resistance is a growing concern in CNS, particularly S. epidermidis, in northern Norway.
    • The increasing prevalence of MRSE necessitates careful antibiotic selection, with vancomycin and rifampicin as reliable options.
    • Continued surveillance of CNS antimicrobial resistance is essential for guiding clinical practice and public health strategies.