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Correlation between ELISA and recombinant immunoblot assay in serum samples positive for anti-HCV
1Department of Obstetrics and Gynecology, National Taiwan University, Taipei, R.O.C.
Abstract:
To determine the false-positivity of antibody to hepatitis C virus (HCV) (anti-C100-3), the correlation between ELISA optical density (OD), anti-HCV titer and recombinant immunoblot assay (RIBA) in 87 anti-HCV-positive sera was analyzed. The results showed that > 90% of the serum samples with an anti-HCV OD > 2.0 or with titers > 10 x were RIBA reactive. These findings are applicable in daily clinical practice.