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Updated: Aug 18, 2026

Electrophysiological Measurements and Analysis of Nociception in Human Infants
Published on: December 20, 2011
Postoperative analgesia: opioid infusions in infants and children
1Department of Anaesthesia, British Columbia's Children's Hospital, Vancouver.
Insights
Traditional pain management for pediatric surgery is ineffective. Advanced methods like IV opioids offer safe and effective postoperative pain relief for children, with specific monitoring for infants.
Area of Science:
- Pediatric Anesthesiology
- Pain Management
- Neonatal Care
Background:
- Acute postoperative pain management in children is often inadequate.
- Infants and children possess the neurological capacity to experience pain similarly to adults.
- Physiological responses to pain are conserved across pediatric and adult populations.
Purpose of the Study:
- To highlight the limitations of traditional pain relief after pediatric surgery.
- To explore pain perception in infants and children.
- To review the application of intravenous opioids for managing postoperative pain in pediatric patients.
Main Methods:
- Review of existing literature on pediatric postoperative pain management.
- Examination of pain sensation in infants and children.
- Description of advanced analgesia techniques, including intravenous opioid administration.
Main Results:
- Traditional analgesic approaches in pediatric surgery are frequently ineffective.
- Advanced techniques such as continuous intravenous opioid infusion and patient-controlled analgesia are effective in pediatric patients.
- Children over six months can safely use these methods with monitoring; infants under six months require high-dependency unit care.
Conclusions:
- Current pediatric postoperative pain management requires significant improvement.
- Intravenous opioid-based strategies, particularly continuous infusions and patient-controlled analgesia, represent a safe and effective advancement.
- Tailored monitoring protocols are essential for optimizing pain management in neonates and young children.
Abstract:
The purpose of this review is to emphasise the ineffectiveness of traditional analgesic therapy in paediatric patients after surgery, to examine the sensation of pain in infants and children, and to describe the use of intravenous opioids for postoperative analgesia. The management of acute postoperative pain in the paediatric surgical population has been poor. This is despite the knowledge that infants and children have sufficient neurological development at birth to sense pain, and that the same hormonal and metabolic responses to nociceptive stimuli that occur in adult also occur in the neonate. Physicians frequently order analgesics in inappropriate doses, nurses are reluctant to administer opioids, and children themselves frequently compound the problem by refusing injections. The sophisticated techniques for providing postoperative analgesia which have been used so successfully in adults can also be used in paediatric patients. Two of these, continuous intravenous opioid infusion and patient-controlled analgesia, have proved to be very successful. Children older than six months can receive either modality safely with regular monitoring by qualified nursing staff. Infants younger than six months receiving continuous opioid infusions should be monitored in high-dependency units.
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