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Takayasu arteritis in India.

B K Sharma1, S Sagar, A P Singh

  • 1Department of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Heart and Vessels. Supplement
|January 1, 1992
PubMed
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Takayasu arteritis is a leading cause of renovascular hypertension in India. This study details its clinical features, diagnosis, and four anatomical patterns in 83 patients, highlighting key diagnostic clues and imaging techniques.

Area of Science:

  • Cardiology
  • Vascular Medicine
  • Rheumatology

Background:

  • Takayasu arteritis is a significant cause of renovascular hypertension in India.
  • Understanding its clinical and radiological spectrum is crucial for timely diagnosis and management.

Purpose of the Study:

  • To describe the clinical and radiological features, complications, and course of Takayasu arteritis in a cohort of Indian patients.
  • To identify diagnostic clues and patterns of the disease.

Main Methods:

  • Retrospective analysis of 83 patients diagnosed with Takayasu arteritis between 1972 and 1990.
  • Clinical evaluation, including symptoms, physical examination (arterial pulses, bruits), and imaging (intravenous urography, aortography).
  • Classification into four anatomical patterns based on disease extent.

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Main Results:

  • Hypertension and associated symptoms like headache were common presentations.
  • Abnormal arterial pulses and bruits were valuable clinical indicators.
  • Intravenous urography showed high sensitivity (80%) for detecting renovascular disease.
  • Four distinct anatomical patterns of arterial involvement were identified.

Conclusions:

  • Takayasu arteritis presents with diverse clinical and radiological features in India.
  • Clinical signs and imaging play vital roles in diagnosis.
  • Recognizing the anatomical patterns aids in understanding disease progression and potential complications.