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Related Experiment Videos

Lichenoid eruption induced by low dose captopril.

S S Wong1, C C Long, P J Holt

  • 1Department of Dermatology, University Hospital of Wales, Cardiff, UK.

Acta Dermato-Venereologica
|September 1, 1992
PubMed
Summary
This summary is machine-generated.

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Captopril, a medication for congestive cardiac failure, can cause a lichenoid drug eruption. This rash resolved on its own after discontinuing the medication.

Area of Science:

  • Dermatology
  • Cardiology
  • Pharmacology

Background:

  • Congestive cardiac failure (CCF) is a chronic condition requiring pharmacologic management.
  • Angiotensin-converting enzyme (ACE) inhibitors, such as captopril, are commonly prescribed for CCF.

Observation:

  • A patient with CCF developed a distinct skin rash during captopril therapy.
  • The rash presented with clinical and histological characteristics of a lichenoid eruption.

Findings:

  • The lichenoid eruption was directly linked to captopril treatment.
  • Cessation of captopril led to spontaneous resolution of the rash within three months.

Implications:

  • This case highlights a potential adverse cutaneous drug reaction to captopril.

Related Experiment Videos

  • Clinicians should consider lichenoid drug eruptions in patients with CCF on ACE inhibitors presenting with similar rashes.
  • Monitoring for dermatologic side effects is crucial in patients receiving captopril.